News & Insights
Mechanism of Increased BK Channel Activation from a Channel Mutation that Causes Epilepsy
February 9, 2009
By: Bin Wang,, Ph.D.
Wang B, Rothberg BS, Brenner R. (2009). Mechanism of increased BK channel activation from a channel mutation that causes epilepsy. J Gen Physiol. 133:283-94.
Hox Repertoires for Motor Neuron Diversity and Connectivity Gated by a Single Accessory Factor, FoxP1
July 25, 2008
By: Bin Wang,, Ph.D.
Dasen JS, De Camilli A, Wang B, Tucker PW, and Jessell TM. (2008). The entire Hox repertoire for motor neuron diversity and connectivity is gated by a single accessory factor, FoxP1...
Oligomerization of STIM1 couples ER calcium depletion to CRAC channel activation
July 24, 2008
By: Bin Wang,, Ph.D.
Luik RM, Wang B (co-first author), Prakriya M, Wu MM, and Lewis RS. (2008). Oligomerization of STIM1 couples ER calcium depletion to CRAC channel activation. Nature 454: 538-42....
An S6 mutation in BK channels reveals beta1 subunit effects on intrinsic and voltage-dependent gating
November 27, 2006
By: Bin Wang,, Ph.D.
Wang B and Brenner R. (2006). An S6 mutation in BK channels reveals beta1 subunit effects on intrinsic and voltage-dependent gating. J Gen Physiol. 128:731-44.
BK channel beta1-subunit regulation of calcium handling and constriction in tracheal smooth muscle
October 1, 2006
By: Bin Wang,, Ph.D.
Semenov I, Wang B, Herlihy JT and Brenner R. (2006). BK channel beta1-subunit regulation of calcium handling and constriction in tracheal smooth muscle. Am J Physiol Lung Cell Mol...
Foxp1 is an essential transcriptional regulator of B cell development
July 2, 2006
By: Bin Wang,, Ph.D.
Hui H, Wang B, Borde M, Maika S, Allred L, Tucker PW and Rao A. (2006). Foxp1 is an essential transcriptional regulator of B cell development. Nat Immunol. 7:819-26. Recommended...
Mechanism of beta4 Subunit Modulation of BK Channels
March 27, 2006
By: Bin Wang,, Ph.D.
• Wang B, Rothberg BS, Brenner R. (2006). Mechanism of beta4 subunit modulation of BK channels. J Gen Physiol. 127:449-65.
Foxp1 regulates cardiac outflow tract, endocardial cushion morphogenesis and myocyte proliferation and maturation
May 27, 2004
By: Bin Wang,, Ph.D.
Wang B, Weidenfeld J, Lu MM, Maika S, Kuziel WA, Morrisey EE, Tucker PW. (2004). Foxp1 regulates cardiac outflow tract, endocardial cushion morphogenesis and myocyte proliferation...