News & Insights
World Trademark Review Recognizes Hamilton Brook Smith Reynolds as a Well-Regarded Boutique
January 2013
Hamilton Brook Smith Reynolds has been once again recognized by World Trademark Review 1000 2013 - The World's Leading Trademark Professionals. "The nimble...
Controlling Costs in Patent Litigation
January 2013
By: John L. DuPré
The following is an excerpt from this article in IAM Magazine's 2013 IP Value - Building and enforcing intellectual property value. Whether you are a patent owner...
Hamilton Brook Smith Reynolds Announces Expansion to the Boston Seaport District
November 5, 2012
Leading intellectual property law firm Hamilton, Brook, Smith & Reynolds, P.C. is pleased to announce that it is expanding from its base in Concord, Massachusetts, to a second...
2011 Innovation Poll Results
Please see below for the results to our 2011 Innovation Poll: Which of the following is the greatest innovation in medicine within the last 200 years? The invention...
An extracellular domain of the accessory 1 subunit is required for modulating BK channel voltage sensor and gate
December 12, 2011
By: Bin Wang,, Ph.D.
Gruslova A, Semenov I and Wang B (corresponding author). (2012). An extracellular domain of the accessory beta1 subunit modulates the voltage sensor and gate of BK channels. J Gen...
U.S. Patent Office Conducts Two Studies Pursuant to the America Invents Act
October 21, 2011
The U.S. Patent and Trademark Office (USPTO) is seeking comments regarding prior user rights and international patent protection for small businesses pursuant to the Leahy-Smith America...
Hamilton Brook Smith Reynolds Recognized as a Top Worldwide Trademark Firm and John L. DuPré Listed as a leading Trademark Practitioner
By: John L. DuPré
Hamilton Brook Smith Reynolds is pleased to announce that we have been named to the Worldwide Trademark Review’s WTR 1000 listing as one of the top firms for trademark matters...
New Challenges and New Opportunities in Enforcing Method of Treatment Claims
July 2011
By: Brian T. Moriarty, Deirdre E. Sanders, and Lawrence P. Cogswell III,, Ph.D.
The U.S. Supreme Court and the Federal Circuit have made and are continuing to make significant changes in the law of multi-party patent infringement – namely, induced infringement...
How the New Multi-Party Patent Infringement Rulings Will Affect Pharmaceutical Treatment Claims
By: Brian T. Moriarty, Deirdre E. Sanders, and Lawrence P. Cogswell III,, Ph.D.
The very recent and continuing focus by the U.S. Supreme Court and the Federal Circuit sitting en banc on multi-party infringement issues – namely, induced infringement and divided...
BK channel beta1 subunits regulate airway contraction secondary to M2 muscarinic acetylcholine receptor mediated depolarization
March 30, 2011
By: Bin Wang,, Ph.D.
Semenov I, Wang B, Herlihy JT and Brenner R. (2011). BK channel beta1 subunits regulate airway contraction secondary to M2 muscarinic acetylcholine receptor mediated depolarization...
Hamilton Brook Smith Reynolds Obtained Patent Linked to Hollywood Film
January 29, 2010
CONCORD, MA, January 29, 2010—The film "Extraordinary Measures" starring Harrison Ford and Brendan Fraser is adapted from the book, The Cure, by Pulitzer Prize winning...
Proepileptic Effects of BK Channel Gene Mutations
December 1, 2009
By: Bin Wang,, Ph.D.
Wang B, Chen, QH, Brenner R. Proepileptic effects of BK channel gene mutations. Encyclopedia of Basic Epilepsy Research. Elsevier Press; 2009.